Source: ANIMAL_MODELS

Gene Uniprot Gene Full Name Protein Class pLI DSI g DPI g Num. diseases
XDH P47989 xanthine dehydrogenase Enzyme 2.6E-22 0.529 0.846 38
TYK2 P29597 tyrosine kinase 2 Kinase 4.5E-08 0.505 0.769 1
TUB P50607 TUB bipartite transcription factor 3.1E-03 0.659 0.385 1
TSC1 Q92574 TSC complex subunit 1 1.00 0.440 0.808 7
TLR4 O00206 toll like receptor 4 4.6E-09 0.321 0.962 41
TGFB1 P01137 transforming growth factor beta 1 Signaling 3.7E-02 0.287 0.962 42
TF P02787 transferrin Enzyme 4.1E-08 0.527 0.846 13
STK11 Q15831 serine/threonine kinase 11 Kinase 0.99 0.435 0.808 8
STAT4 Q14765 signal transducer and activator of transcription 4 Nucleic acid binding 0.77 0.471 0.769 7
STAT3 P40763 signal transducer and activator of transcription 3 Nucleic acid binding 1.00 0.320 0.923 24
SREBF2 Q12772 sterol regulatory element binding transcription factor 2 0.21 0.566 0.577 9
SRD5A1 P18405 steroid 5 alpha-reductase 1 Enzyme 1.2E-05 0.631 0.538 7
SOCS3 O14543 suppressor of cytokine signaling 3 Enzyme modulator 0.75 0.434 0.808 9
SOCS1 O15524 suppressor of cytokine signaling 1 Enzyme modulator 0.59 0.445 0.808 3
SNAP25 P60880 synaptosome associated protein 25 Transporter 0.99 0.489 0.808 4
SLC9A3 P48764 solute carrier family 9 member A3 Transporter 0.98 0.612 0.615 4
SLC27A1 Q6PCB7 solute carrier family 27 member 1 2.6E-16 0.711 0.423 7
SLC10A1 Q14973 solute carrier family 10 member 1 Transporter 4.8E-16 0.626 0.462 4
SIRT6 Q8N6T7 sirtuin 6 Epigenetic regulator 3.9E-02 0.496 0.846 7
SIRT3 Q9NTG7 sirtuin 3 Epigenetic regulator 1.6E-04 0.488 0.731 10
SIRT1 Q96EB6 sirtuin 1 Epigenetic regulator 8.7E-02 0.378 0.885 23
SIM1 P81133 SIM bHLH transcription factor 1 Transcription factor 1.00 0.626 0.654 1
SFTPB P07988 surfactant protein B 2.6E-04 0.575 0.654 6
SFTPA1 Q8IWL2 surfactant protein A1 3.7E-04 0.546 0.808 6